He managed to make the right first impression by securing Tottenham’s first away win in the Premier League since January with a 3-2 victory at West Ham on Saturday that was far more comprehensive that the scoreline suggested.A vital three points cut the gap between Mourinho’s men and the top four to nine points, but strong starts from Liverpool, Leicester, Manchester City and Chelsea mean one of them will have to falter significantly in the coming months to open the door to Spurs.The fact that Mourinho’s deal signed last week reportedly contains a £2 million bonus for making the top four is an illustration of how tough a task it will be.Could winning the Champions League for the first time in the club’s history actually be Spurs’ best way to secure the riches and prestige of Europe’s premier club competition for a fifth consecutive season?Under Mauricio Pochettino, who was sacked after five-and-a-half years in charge last week, Tottenham improved each year in Europe and last season fell just one hurdle short after a dramatic run to Champions League final.Despite their dreadful domestic form and a 7-2 thrashing at home to Bayern Munich last month, Pochettino left with his side well-placed to reach the last 16 once more.Victory over Olympiakos in Mourinho’s home debut on Tuesday will secure their passage into the knockout stages.“I think we can go and win that match at home and qualify in the Champions League,” said Mourinho, who has a proud record of always qualifying from the Champions League group stages in spells as Porto, Chelsea, Inter Milan, Real Madrid and Manchester United.A rejuvenated Spurs could certainly cause problems for some of Europe’s more fancied sides come the new year as they showed in shocking City and Ajax on their way to last season’s final.– Negative approach –Mourinho labelled himself “humble” on his return to management after 11 months out of the game last week, but was quick to point out in his first media briefing that, unlike Tottenham, he had never lost a Champions League final.Glorious past: The second of Jose Mourinho’s two Champions League wins came 10 seasons ago with Inter Milan © AFP / CHRISTOPHE SIMONHe has lifted the trophy twice, with Porto and Inter, but the second of those successes came 10 seasons ago and there are questions over whether he is still the man to deliver Champions League glory.The 56-year-old has failed to win a single knockout tie in the Champions League over the past five years.The nadir of that run came when the negative approach that has often characterised Mourinho’s sides came undone for Manchester United against Sevilla in the last 16 of the 2017/18 season.That style contrasts sharply with the thrilling comebacks away from home that carried Spurs to the final in June as they scored three times in Manchester and Amsterdam.“Before teams just defended and used the counter-attack, now most of the teams have the courage to play,” said City manager Pep Guardiola, after seeing a fearless Chelsea under Frank Lampard go to the Etihad and have secure more possession than the English champions on Saturday.“Young managers, they have nothing to lose, go forward and that’s why the football is nice.”Attack has tended to beat defence in the latter stages in recent years with attack-minded Bayern Munich, Real Madrid, Barcelona and Liverpool the only sides to lift the Champions League in the past seven seasons.Spurs could not have chosen a more different approach. Now they have to see if Mourinho is still capable of Champions League miracles.0Shares0000(Visited 10 times, 1 visits today) 0Shares0000Off to a flyer: Jose Mourinho won his first match in charge of Tottenham © AFP / Adrian DENNISLONDON, United Kingdom, Nov 25 – Tottenham turned to Jose Mourinho to try and maintain their status as a Champions League club, but a terrible start to the Premier League season leaves the Portuguese with a mountain to climb either domestically or in Europe.Mourinho’s appointment was not a universally popular one with the Spurs’ support given his past as a two-time Chelsea manager.
Scientists at Vanderbilt University may have been trying to explain chemical evolution, but hit on another reason DNA is the ideal molecule for carrying genetic information (see also Science Daily). They tweaked the sugar molecule on the DNA backbone and got an unwieldy, haphazard, writhing ribbon of a molecule, unsuitable for bonding genetic code or compacting into chromosomes. It wasn’t even close to DNA. “Just how nature arrived at this molecule and its sister molecule, RNA, remains one of the greatest – and potentially unsolvable – scientific mysteries,” the article says. Martin Egli and team coaxed DNA to incorporate six-carbon sugars instead of the less-common five-carbon sugars (deoxyribose in DNA, and ribose in RNA). What they got is called homo-DNA. Though first synthesized in 1992, homo-DNA had not been studied in structural detail till now. Despite being thermodynamically more favorable for spontaneous formation, homo-DNA is too bulky, and too careless in its base pairing, to be useful as a genetic molecule. Furthermore, it cannot pair with other molecules like RNA – essential for transcription and translation.These researchers did worthwhile work helping us understand why DNA is so good, seemingly “the work of an accomplished sculptor” as well as programmer. “The new insights provided by this structure lie at the heart of the most fundamental of scientific inquiries – the origin of life on Earth,” they said. That’s a worthy question to think about, even if an “unsolveable” mystery from a materialist standpoint. But the press release easily wins Stupid Evolution Quote of the Week for these groaners:DNA’s simple and elegant structure – the “twisted ladder,” with sugar-phosphate chains making up the “rails” and oxygen- and nitrogen-containing chemical “rungs” tenuously uniting the two halves – seems to be the work of an accomplished sculptor. Yet the graceful, sinuous profile of the DNA double helix is the result of random chemical reactions in a simmering, primordial stew.“These molecules are the result of evolution,” said Egli, professor of Biochemistry. “Somehow they have been shaped and optimized for a particular purpose.”“Homo-DNA is just one alternative system. There are hundreds of sugars, as many as you can think of. It will be almost impossible to look at all of them,” Egli said. “But the big red herring of this work could be that nature never went through these other sugars. Maybe it just hit on gold (these five-carbon sugars) very early and took off from there.”This shows that even misguided evolutionary scientists, though hopeless gamblers, are not completely out of touch with reality. Like the blindfolded, they occasionally bump into it and bang their heads. Nobody is forcing them to wear the blindfolds.(Visited 8 times, 1 visits today)FacebookTwitterPinterestSave分享0
The New York Marathon will go ahead as scheduled on Sunday despite the huge damages from Superstorm Sandy, New York Mayor Michael Bloomberg has said.Marathon officials were proceeding as planned to stage the annual event that runs through all five boroughs of the largest city in America, but they were awaiting the final word from city officials regarding the staging of the race, reports Xinhua.Flooding and power outages remained a concern around the city and subway and other transit systems are still shut because of the damage caused by the superstorm.Mary Wittenberg, president of the New York Road Runners, said the organising group was set to hire private contractors to replace city workers who would typically handle such things as security and medical needs for the race.Meanwhile, Elite Kenyan runners supposed to participate in the marathon have delayed their departure, awaiting confirmation that it was safe for them to fly to New York.According to Athletics Kenya president Isaiah Kiplagat, the federation was awaiting communication from organisers after the city was ravaged by Sandy on Monday.”They are still around (in Nairobi) waiting to be told of their travelling plans and I can confirm none of them has left the country yet,” Kiplagat said.”We expect communication by Thursday so that we can be certain that our athletes will be safe. What happened there is very unfortunate and we understand the pain organisers are going through.”Berlin marathon champion Geoffrey Mutai said they were concerned about their chances of making it in time. “I have seen what happened there on television and it was a huge blow to the city. My colleagues left here (Eldoret) Tuesday but I understand their flights were held back.”advertisement